Osimert 80 is used to treat adult patients with certain EGFR mutations. Make sure to take it every day to get the most benefit. Your doctor will determine what dose you need and how often you should take Osimert. It depends on what you are being treated for and may change from time to time. You should take Osimert 80 exactly as your doctor has told you. Taking too much or too little can cause very serious side effects. It may take weeks or months for you to see or feel the benefits. However, do not stop taking Osimert 80 unless your doctor tells you to. One of this medication’s most frequent negative effects is diarrhea. So drink plenty of fluids. However, if your doctor does not stop, you should inform him. If you have a fever, cough, or difficulty breathing along with peeling skin, you should inform your doctor.
Osimertinib 80 mg price
Osimert 80 mg is a medication produced by IEB Pharma. Primarily used for treating metastatic non-small cell lung cancer (NSCLC) with specific EGFR mutations. In Bangladesh, the retail price for a pack of 30 tablets is ৳12,750, equating to ৳425 per tablet. For purchasing Osimert 80 mg, you can consider local pharmacies or reputable online platforms like ePharma, which offers the product at a discounted price of ৳12,240 for a 30-tablet pack.
How to use Osimert 80
Swallow it whole. Do not chew, crush or break it. Osimert 80 can be taken with or without food, but it is best to take it at a specific time.
How Osimert 80 works
Osimert 80 is an anti-cancer medicine. It works by blocking the action of abnormal proteins that signal cancer cells to multiply.
What if you forget to take Osimert 80?
If you miss a dose of Osimert 80, skip it and go back to your normal schedule. Do not double the dose.
Osimert 80 is used to treat thyroid cancer.
Diarrhea may occur as a side effect. Drink plenty of fluids and tell your doctor if it does not stop, or if you notice blood in your stool. Use reliable birth control to prevent pregnancy while taking this medicine and for one month after it is stopped. If you experience symptoms of very high blood pressure, such as severe headache, confusion, vision problems.
This can cause serious bleeding problems. Tell your doctor if you have a headache or stomach pain or notice blood in your urine or stool.
Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding.
Indications
For the treatment of patients with metastatic non-small cell lung cancer (NSCLC) that has an epidermal growth factor receptor (EGFR) T790M mutation.
Administration
Do not swallow, crush/squash/bite. In patients with difficulty swallowing, the tablets should be dispersed in 50 ml of water and should not be crushed until dissolved. Drink immediately. Rinse the glass with another glass of water and drink. The dispersed liquid can also be administered through a NasogATR tube using an initial 15 ml dispersion and a 15 ml residue. The tubes should be flushed with water after administration. The solution be administer 30 minutes after adding the tablets to the water.
Pediatric Dosage
Safety and efficacy not established
Renal Dosage
Mild to moderate renal impairment (CrCl 30-89 mL/min): No dose adjustment required Severe or ESRD (CrCl <30 mL/min): No recommended dose
Side effects
interstitial lung disease (ILD)/pneumonitis – Can be life-threatening; Symptoms include cough, fever, and breathing difficulties.
Cardiac issues (QT prolongation) – May increase the risk of arrhythmias.
Decreased heart function (heart failure) – Monitor for symptoms like shortness of breath and swelling in the legs.
Liver toxicity – Elevat liver enzymes (ALT/AST); Regular liver function tests are recommend.
Blood disorders – Including reduced white blood cell or platelet counts.
Eye disorders – Blurred vision, dry eyes, or eye inflammation.
Interaction
Osimertinib 80 mg decreased exposure w/ strong CYP3A4 inducers (eg, phenytoin, rifampicin, carbamazepine, St. John’s wort). May increase AUC & Cmax of rosuvastatin. This may increase the exposure of BCRP substrates.
